Moleculare Virology: Onkogenic viruses

Zeit: Mo. 18:00-19.00, seminar room,BMFZ, Schillingallee 69

Semester: SS

Dozent(en): Prof. B.M. Pützer

Beschreibung: What are oncogenes and anti-oncogenes? Which viruses can cause cancer in man? What are the differences between DNA- and RNA-tumor viruses? How do DNA- and RNA-viruses transform a cell? There are seven viruses known to cause cancer in humans. The group comprises several Human Papilloma Viruses (HPV), the Hepatitis B (HBV) and the Hepatitis C Virus (HCV), theEpstein-Barr Virus (EBV), the Human Herpesvirus 8 / Kaposi Sarkom-assoziierte Virus (HHV8/KSHV), the Humane T-lymphotrope Virus I (HTLV-I and -II) and the Merkel Cell Carcinoma Virus (MCPyV). This seminar deals with the mechanisms with which these viruses promote cancer onset. Further, the classification, transmission, diagnostics of HPV and the role of individual HPSs in pre-malign leasions of the cervix, the cervical carcinoma and the penile carcinoma are carved out. Finally, the epidemiology of HTLV-I and -II is reiterated as well as these viruses’ role in the emergence of the Adult T-cell lymphoma

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