Novel Viral Vectors for Gene Therapy

Ottmar Herchenröder, Brigitte Pützer
Viral vectors are gene transfer tools assembled from the backbones of naturally occurring viruses. By definition, these vehicles that transfer nucleic acids are replication-incompetent but deliver assigned payloads into eukaryotic cells by a process called transduction. For decades, numerous viral vector systems that influence cells or tissues have been used to perform basic and preclinical research. Over time, some virus-derived vectors found their way into clinical practice.
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