Neueste Publikation


    Oncotarget. 2014 Mar 21
    Eradication of metastatic melanoma through cooperative expression of RNA-based HDAC1 inhibitor and p73 by oncolytic adenovirus.

    Schipper H, Alla V, Meier C, Nettelbeck DM, Herchenröder O, Pützer BM.

    Abstract

    Malignant melanoma is a highly aggressive cancer that retains functional p53 and p73, and drug unresponsiveness largely depends on defects in death pathways after epigenetic gene silencing in conjunction with an imbalanced p73/DNp73 ratio. We constructed oncolytic viruses armed with ...

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Prof. Dr. med. Dr. rer. nat

 Brigitte M. Pützer

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