European Urology Focus
E2F1 Signalling is Predictive of Chemoresistance and Lymphogenic Metastasis in Penile Cancer: A Pilot Functional Study Reveals New Prognostic Biomarkers.
Fenner F, Goody D, Protzel C, Erbersdobler A, Richter C, Hartz JM, Naumann CM, Kalthoff H, Herchenröder O, Hakenberg OW, Pützer BM.
Background: For penile cancer (PC) there are no known molecular predictors of lymphatic spread and/or chemoresistance. Objective: To identify functional biomarkers that can predict malignant progression and treatment responsiveness. Design, setting, and participants: We used four patient-derived PC cell lines ...